A newly developed HPLC-MS/MS assay according to the EMA guideline for bioanalytical validation for determination of Estriol, Estradiol, and Estrone at pharm-analyt is now capable of directly (= underivatised) determining the three substances in human plasma to LLOQs of 1 pg/mL, 3 pg/mL, and 5 pg/mL respectively. Sample preparation used is quite simple which is liquid-liquid extraction; the assay was validated using ESI in negative ion mode on an API 6500 QTrap in combination with the ion mobility device Selexion. Benefits of an HPLC-MS/MS method over any kind of immuno-assay are well known and are primarily related to selectivity issues where immuno-assays often have difficulties with (key word: cross-reactivity).

With the most recent publication (Annals of Laboratory Medicine), pharm-analyt´s team has co-authored 100 publications in peer reviewed journals (Total impact factor >200)!

An inquisitive corporate culture is bound to challenge conventional approaches, leading to new ways and discoveries. If valuable for the community these ought to be published.

Most of our publications are submitted in collaboration with our partners / sponsors and related to a recent specific project or task. So “real live topics”. Some publications derive from our own research work, for instance in the field of biomarkers.
You find a comprehensive overview over all our publications under: R&D Publications or www.pharm-analyt.com/index.php/r-d.

Though self evident, it is emphasized at this point, that nothing is published without approval of the relevant stakeholders.

October 2013

This year we won´t be travelling far, as the annual international partnering conference will be held in Vienna!

We are looking forward to meeting many of you and to take the opportunity to invite you to visit our facility in Baden, just south of Vienna at this occasion!

See you soon, in Vienna!

September 2013   –  

pharm-analyt officially launched its new website, introducing the updated corporate design

The website was entirely re-engineered to give a quick, yet comprehensive overview of pharm-analyt´s scope of services and special skills. The clear user interface provides easier, more intuitive orientation and efficient navigation. Playful and entertaining aspects take the visitor beyond mere functionality: Encounter curiosity and creativity in a highly regulated environment. The new look and selective use of colors hint at our new corporate design.