Individualization of medicine calls for biomarkers. Our research cooperations have proven that Small Molecules (and peptides) can be very effective indicators.
Several biomarkers showed nearly 100% specificity and 100% sensitivity. This work resulted in patents and industrial licensing agreements.
EP 2 533 051 (Gaucher: Lysosomal Storage Disease)
EP 11 009 062.8 (NPC Niemann-Pick Disease)
EP 12 008 257.3 (MLD Metachromatic Leukodystrophy)
Example ROC-Curve for Lyso GB1 (Source: Patent EP 2 533 051 A1):