Third European Patent for Biomarker Submitted!

Tuesday, 01 January 2013 More News

After submitting european patents for lysosomal storage deseases in 2011 (Gaucher) and 2012 (NPC) in December last year we submitted another patent for a marker for MLD!

All three markers have remarkably high sensitivity as well as specificity.
pharm-analyt is continuously investigating in biomarkers, predominantly Small Molecules in plasma.

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Did you know:

We are

locals

in the area of trace analysis.
pharm-analyt has discovered biomarkers that will save

the lives of thousands of children

suffering from various rare diseases.
pharm-analyt requires as little as

50 µL

sample volume for clinical studies,
if necessary.
Throughout the

35 years

of pharm-analyt’s existence it
was always equipped with
state-of-the-art instrumentation.
Every day

we are learning something
about bioanalysis.
50 %

of the analytical know-how lies
in sample preparation.
pharm-analyt has developed bioanalytical assays for more than

400 compounds.
We are

giving away

a lot of our know-how in Hermann’s book “HPLC Methods for Clinical Pharmaceutical Analysis”.

(See R&D)
A quote from one of our collaborators concerning PEG tissue analysis: I am totally blown away by the fact that not only do you have measurable levels of PEG

but they are also dose-dependent!!

Amazing stuff!!
Inpassible…? Imposibol…? Unpossibal…?

Sorry, we’re just not
familiar with this word.
Metabolite profiling is a matter of

a few days,

not months.
Our most sensitive method has an LLOQ of

0.00000000000025

g/mL plasma.

= 250 femtogram/mL
or 250 x 10^-15 g/mL
or 1 kg sugar in lake Chiemsee!
pharm-analyt is

fully family-owned.
pharm-analyt has over

100 publications

in peer reviewed journals.
pharm-analyt was founded

long before

mass spec was widespread.
pharm-analyt has won

several awards

for innovation.
You will get the clinical PK profile of

250

common drugs from us for free.

Contact us.
pharm-analyt has been
GLP certified for almost

30 years.
pharm-analyt has developed
multiple ways of

stabilizing peptides

in plasma.
Why our founder’s

hairstyle

sometimes reminds of a well known nuclear physicist? Tell us if you know!
We are

always eager
for difficult analytical challenges.
“Edelweiss”

is not the Austrian anthem.
It is our national flower.
We work, where the

Austrian Emperors

went on vacation.

(Historical town of Baden)
"Never give in,
never, never
never, never, in nothing great or small."
(Sir Winston Churchill)
In a number of cases chemical

derivatization

might be the key to
success in bioanalysis.
They say

it’s not feasible?

Give us a try.
pharm-analyt conducts

25

(bio)-analytical feasibility
studies each year.
Rumors say:

…Of all of our equipment, the
highest throughput is with our

espresso machine?!
Rumors say:

…For a remarkable bottle of

Chardonnay,

our founder Hermann Mascher would conduct the analysis of a large clinical study for free. :-)
A part of our historical
premises used to be a

bakery

before we moved in.
pharm-analyt was

one of the first

CROs to switch to electronic archiving.
Our first look might be

invaluable

and it’s for free!
pharm-analyt has sold

3 European patents

on biomarkers.

›

‹

locals

the lives of thousands of children

50 µL

35 years

Every day

50 %

400 compounds.

giving away

but they are also dose-dependent!!

Inpassible…? Imposibol…? Unpossibal…?

a few days,

0.00000000000025

fully family-owned.

100 publications

long before

several awards

250

30 years.

stabilizing peptides

hairstyle

always eager

“Edelweiss”

Austrian Emperors

never, never

derivatization

it’s not feasible?

25

espresso machine?!

Chardonnay,

bakery

one of the first

invaluable

3 European patents